Special Concerns in Defining, Studying, and Treating Dystonia in Children
Identifieur interne : 000773 ( Main/Exploration ); précédent : 000772; suivant : 000774Special Concerns in Defining, Studying, and Treating Dystonia in Children
Auteurs : Jonathan W. MinkSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2013.
English descriptors
- KwdEn :
- MESH :
- diagnosis : Dystonia.
- therapy : Dystonia.
- Animals, Child, Humans, Pediatrics, Sex Factors.
Abstract
Dystonia is movement disorder with many diverse underlying etiologies. Some of those etiologies manifest at specific stages of development or at specific ages. Others may present early in life and evolve as the individual develops. Appearance of symptoms during a time of nervous system development poses special challenges to the neurology. Normal functions change appearance, dysfunction may manifest in an age-dependent manner, and age-dependent differences in beneficial and toxic effects of treatments all introduce complexities to the process of diagnosis, functional assessment, and therapeutics. Consideration of these developmental differences is essential in assuring a universal definition of dystonia, valid and reliable assessment tools that can be compared across the lifespan, and more effective therapeutics.
Url:
DOI: 10.1002/mds.25548
PubMed: 23893449
PubMed Central: 3806453
Affiliations:
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Le document en format XML
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